Recombinant Mouse Col1a1 protein, His-tagged

• Cat.No.: Col1a1-08M
• Product Overview: Recombinant Mouse Col1a1 fused with His tag was expressed in HEK293.

Specification

• Description: This gene encodes the alpha-1 subunit of the fibril-forming type I collagen, the most abundant protein of bone, skin and tendon extracellular matrices. The encoded protein, in association with alpha-2 subunit, forms heterotrimeric type I procollagen that undergoes proteolytic processing during fibril formation. Mice lacking the encoded protein die in utero caused by the rupture of a major blood vessel. Transgenic mice expressing significantly lower levels of this gene exhibit morphological and functional defects in mineralized and non-mineralized connective tissue and, progressive loss of hearing.
• Source: HEK293
• Species: Mouse
• Tag: His
• Form: Tris-based buffer, 50% glycerol
• Purity: >90% (SDS-PAGE)
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade.

Gene Information

• Gene Name: Col1a1 collagen, type I, alpha 1 [ Mus musculus ]
• Official Symbol: Col1a1
• Synonyms: COL1A1; collagen, type I, alpha 1; collagen alpha-1(I) chain; alpha-1 type 1 collagen; alpha-1 type I collagen; procollagen, type I, alpha 1; Cola1; Mov13; Cola-1; Mov-13; Col1a-1
• Gene ID: 12842
• mRNA Refseq: NM_007742
• Protein Refseq: NP_031768
• UniProt ID: P11087
• Chromosome Location: 11 59.01 cM; 11 D
• Pathway: Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Axon guidance, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Developmental Biology, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem
• Function: extracellular matrix structural constituent; identical protein binding; platelet-derived growth factor binding; protein binding