Recombinant Mouse Chemokine(C-C motif) Ligand 17

• Cat.No.: Ccl17-625M
• Product Overview: A DNA sequence encoding the mouse Ccl17 (Met 1-Pro 93) was expressed and purified. It consists of 73 amino acids and has a predicted molecular mass of 8.2 kDa.

Specification

• Species: Mouse
• Source: Human Cells
• Tag: Non
• Protein Length: 73aa
• Description: Ccl17 is a secreted protein which belongs to the?intercrine beta (chemokine CC) family. Chemokines are known to regulate the steady-state and inflammatory migration of cutaneous dendritic cells (DCs). The beta-chemokine Ccl17, a ligand of CCR4, is inducibly expressed in a subset of DCs and is strongly up-regulated in atopic diseases.
• Predicted N Terminal: Ala 21
• Form: Lyophilized from 0.2μm filtered solution of PBS, pH7.5. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
• Molecular Mass: The secreted pro form of recombinant mouse Ccl17 consists of 73 amino acids and has a predicted molecular mass of 8.2KDa as estimated in SDS-PAGE under reducing conditions.
• Endotoxin: 1.0 eu/μg of the protein as determined by the lal
• Purity: >98 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70 °C.
• Storage: Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: Ccl17 chemokine (C-C motif) ligand 17 [ Mus musculus ]
• Official Symbol: Ccl17
• Synonyms: CCL17; chemokine (C-C motif) ligand 17; small inducible cytokine subfamily A17; Tarc; Abcd-2; Scya17; Scya17l
• Gene ID: 20295
• mRNA Refseq: NM_011332
• Protein Refseq: NP_035462
• Pathway: Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem
• Function: CCR4 chemokine receptor binding; chemokine activity; cytokine activity