Recombinant Mouse Brk1 Protein, MYC/DDK-tagged

• Cat.No.: Brk1-178M
• Product Overview: Purified recombinant protein of full-length mouse BRICK1, SCAR/WAVE actin-nucleating complex subunit (Brk1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.
• Molecular Mass: 9.2 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Brk1 BRICK1, SCAR/WAVE actin-nucleating complex subunit [ Mus musculus (house mouse) ]
• Official Symbol: Brk1
• Synonyms: Brk1; BRICK1, SCAR/WAVE actin-nucleating complex subunit; AW011779; 6720456B07Rik; protein BRICK1; probable protein BRICK1
• Gene ID: 101314
• mRNA Refseq: NM_133937
• Protein Refseq: NP_598698
• UniProt ID: Q91VR8