Recombinant Mouse Aspa Protein, His-tagged

• Cat.No.: Aspa-253M
• Product Overview: Recombinant Mouse Aspa Protein (Tyr63-His312) with N-His tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Tyr63-His312
• Description: This gene encodes an enzyme that deacteylates N-acetyl-L-aspartic acid (NAA) in the brain to yield acetate and L-aspartate. In humans, alterations in neuronal NAA concentration are associated with many neurodegenerative diseases (decrease associated with epilepsy, multiple sclerosis, myotrophic lateral sclerosis, and Alzheimer's disease; increase associated with Canavan disease). In mouse, mutations in this gene, which cause accumulation of NAA, result in demyelination and spongy degeneration in the CNS and serve as a pathophysiological model for Canavan disease.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 32.2 kDa
  Accurate Molecular Mass: 32 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Aspa aspartoacylase [ Mus musculus (house mouse) ]
• Official Symbol: Aspa
• Synonyms: ASPA; aspartoacylase; aminoacylase 2; aminoacylase-2; small lethargic; aspartoacylase (aminoacylase) 2; Acy2; nur7; Acy-2
• Gene ID: 11484
• mRNA Refseq: NM_023113
• Protein Refseq: NP_075602
• UniProt ID: Q8R3P0