Recombinant Mouse Apaf1 protein, His-tagged

• Cat.No.: Apaf1-1755M
• Product Overview: Recombinant Mouse Apaf1(Arg872~Phe1135) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Arg872~Phe1135
• Description: Apaf1 played an important role in many functions.
• Form: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Molecular Mass: 30.9kDa
• AA Sequence: MGHHHHHHSGSEF- RLKVADCRG HLSWVHGVMF SPDGSSFLTA SDDQTIRVWE TKKVCKNSAI VLKQEIDVVF QENETMVLAV DNIRGLQLIA GKTGQIDYLP EAQVSCCCLS PHLEYVAFGD EDGAIKIIEL PNNRVFSSGV GHKKAVRHIQ FTADGKTLIS SSEDSVIQVW NWQTGDYVFL QAHQETVKDF RLLQDSRLLS WSFDGTVKVW NVITGRIERD FTCHQGTVLS CAISSDATKF SSTSADKTAK IWSFDLLSPL HELKGHNGCV RCSAF
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Apaf1 apoptotic peptidase activating factor 1 [ Mus musculus ]
• Official Symbol: Apaf1
• Synonyms: APAF1; apoptotic peptidase activating factor 1; apoptotic protease-activating factor 1; forebrain overgrowth; apoptotic protease activating factor 1; fog; Apaf-1; Apaf1l; mKIAA0413; 6230400I06Rik; KIAA0413
• Gene ID: 11783
• mRNA Refseq: NM_001042558
• Protein Refseq: NP_001036023
• UniProt ID: O88879
• Chromosome Location: 10 45.47 cM; 10 C3-D1
• Pathway: Activation of caspases through apoptosome-mediated cleavage, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem
• Function: ADP binding; ATP binding; apoptotic protease activator activity; heat shock protein binding; identical protein binding; identical protein binding; nucleotide binding