Recombinant Mouse Aldh6a1 Protein, MYC/DDK-tagged

• Cat.No.: Aldh6a1-267M
• Product Overview: Purified recombinant protein of full-length mouse aldehyde dehydrogenase family 6, subfamily A1 (Aldh6a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded enzyme is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This enzyme catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Mutations in the human gene result in Methylmalonate Semialdehyde Dehydrogenase Deficiency, characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants encoding different isoforms.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 58 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Aldh6a1 aldehyde dehydrogenase family 6, subfamily A1 [ Mus musculus (house mouse) ]
• Official Symbol: Aldh6a1
• Synonyms: Aldh6a1; aldehyde dehydrogenase family 6, subfamily A1; Mmsdh; 1110038I05Rik; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; aldehyde dehydrogenase family 6 member A1; malonate-semialdehyde dehydrogenase; EC 1.2.1.18; EC 1.2.1.27
• Gene ID: 104776
• mRNA Refseq: NM_134042
• Protein Refseq: NP_598803
• UniProt ID: Q9EQ20