Recombinant Human Aldehyde Dehydrogenase 6 Family, Member A1, GST-tagged

• Cat.No.: ALDH6A1-501H
• Product Overview: Recombinant Human ALDH6A1protein was expressed as gst-tagged fusion protein by E. coli and purified byGSH-sepharose. The purified protein was resolved in 1M PBS (58mM Na2HPO4, 17mMNaH2PO4, 68mM NaCl, pH8.) added with 100mM GSH and 1% TritonX-100,15%glycerol.

Specification

• Cat. No.: ALDH6A1-501H
• Description: ALDH6A1 belongs tothe aldehyde dehydrogenases family of proteins. ALDH6A1 plays a role in the valineand pyrimidine catabolic pathways. Methylmalonate semialdehyde dehydrogenasedeficiency is characterized by elevated beta-alanine, 3-hydroxypropionicacid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urineorganic acids.
• Host: E. coli
• Antigen peptideregion: C-342aa
• Full length: False
• Storage: Theprotein is stored in PBS buffer at -20°C.Repeated freeze-thaw cycles should be avoided.

Gene Information

• Gene Name: ALDH6A1 aldehyde dehydrogenase 6family, member A1 [ Homo sapiens ]
• Official Symbol: ALDH6A1
• Synonyms: ALDH6A1;aldehyde dehydrogenase 6 family, member A1; MMSDH; MMSADHA; MGC40271;methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial;malonate-semialdehyde dehydrogenase; aldehyde dehydrogenase family 6 memberA1; mitochondrial acylating methylmalonate-semialdehyde dehydrogenase; EC1.2.1.18; EC 1.2.1.27
• Gene ID: 4329
• mRNA Refseq: NM_005589
• Protein Refseq: NP_005580
• MIM: 603178
• UniProt ID: Q02252
• Chromosome Location: 14q24.3
• Pathway: Branched-chain aminoacid catabolism; Inositol phosphate metabolism; Malonate semialdehydepathway; Metabolic pathways; Metabolism; Metabolism of amino acids andderivatives; Propanoate metabolism; Valine; beta-Alanine metabolism;beta-alanine degradation I; valine degradation I
• Function: fatty-acyl-CoAbinding; malonate-semialdehyde dehydrogenase (acetylating) activity;methylmalonate-semialdehyde dehydrogenase (acylating) activity;oxidoreductase activity