Recombinant Human UBE2J2 Protein, His-tagged

• Cat.No.: UBE2J2-244H
• Product Overview: Recombinant Human UBE2J2(Glu124-Arg224), transcript variant 2, fused with His tag at C-terminal was expressed in E. coli.

Specification

• Description: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 20mM Phosphate buffer, 150mM NaCl, 1mM DTT, pH 7.2. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 38 kDa
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Protein length: 124-224 a.a.

Gene Information

• Gene Name: UBE2J2 ubiquitin-conjugating enzyme E2, J2 [ Homo sapiens ]
• Official Symbol: UBE2J2
• Synonyms: UBE2J2; ubiquitin-conjugating enzyme E2, J2; ubiquitin conjugating enzyme E2, J2 (UBC6 homolog, yeast); ubiquitin-conjugating enzyme E2 J2; NCUBE2; Ubc6p; yeast UBC6 homolog; ubiquitin conjugating enzyme 6; ubiquitin conjugating enzyme E2, J2; non-canonical ubiquitin-conjugating enzyme 2; ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast); NCUBE-2; PRO2121
• Gene ID: 118424
• mRNA Refseq: NM_058167
• Protein Refseq: NP_477515
• UniProt ID: Q8N2K1