Recombinant Human TYRP1 Protein, His-tagged

• Cat.No.: TYRP1-512H
• Product Overview: Recombinant human TYRP1 (P17643) extracellular domain (Met 1- Arg 471) was fused with a polyhistidine tag at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 1-471 a.a.
• Predicted N Terminal: Gln 25
• Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
• Molecular Mass: The secreted recombinant human TYRP1 comprises 458 amino acids and has a predicted molecular mass of 52.2 kDa. The apparent molecular mass of rh TYRP1 is approximately 66 kDa in SDS-PAGE under reducing conditions due to glycosylation.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >95 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: TYRP1 tyrosinase-related protein 1 [ Homo sapiens ]
• Official Symbol: TYRP1
• Synonyms: TYRP1; tyrosinase-related protein 1; CAS2, TYRP; 5,6-dihydroxyindole-2-carboxylic acid oxidase; b PROTEIN; CATB; GP75; TRP; TRP1; TRP-1; catalase B; DHICA oxidase; glycoprotein 75; melanoma antigen gp75; CAS2; TYRP; b-PROTEIN
• Gene ID: 7306
• mRNA Refseq: NM_000550
• Protein Refseq: NP_000541
• MIM: 115501
• UniProt ID: P17643
• Chromosome Location: 9p23
• Pathway: Direct p53 effectors, organism-specific biosystem; Melanogenesis, organism-specific biosystem; Melanogenesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; Tyrosine metabolism, organism-specific biosystem; Tyrosine metabolism, conserved biosystem; ethanol degradation IV, organism-specific biosystem