Description :	The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
Source :	HEK293
Species :	Human
Tag :	Myc&DDK
Form :	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass :	58.3 kDa
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration :	>50 ug/mL as determined by microplate BCA method

Gene Name	TYR tyrosinase (oculocutaneous albinism IA) [ Homo sapiens ]
Official Symbol	TYR
Synonyms	ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3
Gene ID	7299
mRNA Refseq	NM_000372
Protein Refseq	NP_000363
MIM	606933
UniProt ID	P14679