Recombinant Human TWIST1 cell lysate

• Cat.No.: TWIST1-1865HCL

Specification

• Species: Human
• Tag: Non
• Description: Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue; in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: TWIST1 twist homolog 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: TWIST1
• Synonyms: TWIST1; twist homolog 1 (Drosophila); acrocephalosyndactyly 3 , ACS3, blepharophimosis, epicanthus inversus and ptosis 3 , BPES3, TWIST; twist-related protein 1; bHLHa38; BPES2; H twist; Saethre Chotzen syndrome; SCS; H-twist; B-HLH DNA binding protein; TWIST homolog of drosophila; class A basic helix-loop-helix protein 38; ACS3; CRS1; BPES3; TWIST
• Gene ID: 7291
• mRNA Refseq: NM_000474
• Protein Refseq: NP_000465
• MIM: 601622
• UniProt ID: Q15672
• Chromosome Location: 7p21
• Pathway: Adipogenesis, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem; Notch-mediated HES/HEY network, organism-specific biosystem
• Function: DNA binding; E-box binding; bHLH transcription factor binding; protein binding; protein domain specific binding; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding RNA polymerase II transcription factor activity; transcription factor binding