Recombinant Human TSHR cell lysate, Myc/DDK-tagged

• Cat.No.: TSHR-717HCL
• Product Overview: Recombinant Human TSHR transient overexpression lysate (as WB positive control) with a C-terminal Myc/DDK tag was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293T
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 86.83 kDa
• Usage: 1 vial of 20 µg lyophilized gene specific transient over-expression cell lysate.
• Stability: Lysate samples are stable for 12 months from date of receipt when stored at -20 centigrade. Lysate samples can be diluted with 2xSDS Sample Buffer provided. After dilution, the protein sample should be aliquoted and stored at -20centigrade for long term storage. Lysate samples are stable for 12 months from date of receipt when stored at -20centigrade.
• Storage: Upon receiving, store the sample at -20 centigrade. Avoid repeated freeze-thaw cycles after reconstitution.

Gene Information

• Gene Name: TSHR thyroid stimulating hormone receptor [ Homo sapiens (human) ]
• Official Symbol: TSHR
• Synonyms: TSHR; thyroid stimulating hormone receptor; LGR3; CHNG1; hTSHR-I; thyrotropin receptor; TSH receptor; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2; thyrotropin receptor-I, hTSHR-I
• Gene ID: 7253
• mRNA Refseq: NM_000369
• Protein Refseq: NP_000360
• MIM: 603372
• UniProt ID: P16473