Recombinant Human TSHR Protein, His-tagged

Cat.No. : TSHR-127H
Product Overview : Recombinant Human TSHR Protein, fused to His-tag, was expressed in E. coli.
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Description : The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
Source : E. coli
Species : Human
Tag : His
Form : 58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.0 added with 300mM Imidazole and 0.7% Sarcosyl, 15% glycerol
Molecular Mass : 27.4 kDa
AA Sequence : MKKGHHHHHHGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLDVSQTSVTALPSKGLEHLKELI
Purity : >90%
Storage : Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Concentration : 1.6 mg/ml
Gene Name TSHR thyroid stimulating hormone receptor [ Homo sapiens (human) ]
Official Symbol TSHR
Synonyms LGR3; CHNG1; hTSHR-I
Gene ID 7253
mRNA Refseq NM_000369
Protein Refseq NP_000360
MIM 603372
UniProt ID P16473

Not For Human Consumption!

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