Recombinant Human TSEN2 Protein, MYC/DDK-tagged

• Cat.No.: TSEN2-2803H
• Product Overview: Recombinant Human TSEN2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 53.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TSEN2 tRNA splicing endonuclease 2 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: TSEN2
• Synonyms: PCH2B; SEN2; SEN2L
• Gene ID: 80746
• mRNA Refseq: NM_001145392
• Protein Refseq: NP_001138864
• MIM: 608753
• UniProt ID: Q8NCE0