Recombinant Human TRPC6 Protein, His-tagged

• Cat.No.: TRPC6-347H
• Product Overview: Recombinant Human TRPC6(Met1~Leu192) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Met1~Leu192
• Description: The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 25kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: TRPC6 transient receptor potential cation channel, subfamily C, member 6 [ Homo sapiens ]
• Official Symbol: TRPC6
• Synonyms: TRPC6; transient receptor potential cation channel, subfamily C, member 6; short transient receptor potential channel 6; TRP6; TRP-6; transient receptor protein 6; FSGS2; FLJ11098; FLJ14863
• Gene ID: 7225
• mRNA Refseq: NM_004621
• Protein Refseq: NP_004612
• MIM: 603652
• UniProt ID: Q9Y210