Recombinant Human Tropomodulin 1, T7-tagged

• Cat.No.: TMOD1-3002H
• Product Overview: Recombinant Human TMOD1 protein was expressed in E.coli with T7-tag at the N-terminus. The molecular weight is 40569 Da(359 aa).

Specification

• Cat. No.: TMOD1-3002H
• Description: Tropomodulin-1 is a protein that in humans is encoded by the TMOD1 gene. Human erythrocyte tropomodulin is a 43-kD tropomyosin-regulating protein. It may modulate the association of tropomyosin with the spectrin-actin complex in the erythrocyte membrane skeleton, and thus the viscoelastic properties of erythrocytes. Tropomodulin is associated with the pointed end of the actin filaments. It binds specifically to the N terminus of tropomyosin and blocks the elongation and depolarization of tropomyosin-coated actin filaments.
• Sequences of amino acids: 1-359 aa
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT.
• Purity: 90%

Gene Information

• Gene Name: TMOD1 tropomodulin 1 [ Homo sapiens ]
• Synonyms: TMOD; ETMOD; D9S57E; E-Tmod; e-tropomodulin; OTTHUMP00000021743; OTTHUMP00000021744; erythrocyte tropomodulin; tropomodulin-1
• Gene ID: 7111
• mRNA Refseq: NM_003275
• Protein Refseq: NP_003266
• MIM: 190930
• UniProt ID: P28289
• Chromosome Location: 9q22.3
• Pathway: Reactome Event:Muscle contraction
• Function: actin binding; tropomyosin binding