Recombinant Human TMOD1, T7 -tagged

• Cat.No.: TMOD1-31624TH
• Product Overview: Recombinant fusion protein: Full lenght human tropomodulin 1 with a T7 tag at N-terminus

Specification

• Description: This gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene.
• Conjugation: T7
• Source: E. coli
• Tissue specificity: Highly expressed in the erythrocyte, heart and skeletal muscle.
• Form: Liquid
• Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton-X-100, 10mM Tris, 10mM DTT, pH 8.0
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the tropomodulin family.

Gene Information

• Gene Name: TMOD1 tropomodulin 1 [ Homo sapiens ]
• Official Symbol: TMOD1
• Synonyms: TMOD1; tropomodulin 1; D9S57E, TMOD; tropomodulin-1; ETMOD
• Gene ID: 7111
• mRNA Refseq: NM_003275
• Protein Refseq: NP_003266
• MIM: 190930
• Uniprot ID: P28289
• Chromosome Location: 9q22
• Pathway: Muscle contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem
• Function: actin binding; tropomyosin binding