TMOD1
-
Official Full Name
tropomodulin 1 -
Overview
This gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene. -
Synonyms
TMOD1;tropomodulin 1;D9S57E, TMOD;tropomodulin-1;ETMOD;D9S57E;E Tmod;E tropomodulin;E-Tmod;Erythrocyte tropomodulin;MGC124125;MGC124126;OTTHUMP00000021743;TMOD;TMOD1 protein;TMOD1_HUMAN;e-tropomodulin
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- T7
- Non
- GST
- Myc&DDK
- His&Fc&Avi
Involved Pathway
TMOD1 involved in several pathways and played different roles in them. We selected most pathways TMOD1 participated on our site, such as Muscle contraction,Striated Muscle Contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TMOD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Muscle contraction | MYBPC2B,SMYHC3,TMOD2,SORBS3,ANXA2,MYBPC1,DESMA,TNNI2A.4,MYBPC2,TMOD3 |
| Striated Muscle Contraction | MYBPC2,DMD,TNNI2B.1,TMOD4,TNNT3B,TMEM8C,MYBPC1,MYL1,MYBPC3,TCAP |
Protein Function
TMOD1 has several biochemical functions, for example, actin filament binding,tropomyosin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TMOD1 itself. We selected most functions TMOD1 had, and list some proteins which have the same functions with TMOD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| tropomyosin binding | TNNT1,LMOD2A,LMOD3,TMOD2,TNNT2A,S100A6,TNNT3,TMOD3,TMOD4,LMOD1 |
| actin filament binding | ACTN4,PKNOX2,BLOC1S6,ADSSL1,SYNE1,WIPF1A,TMEM201,ADD1,JUB,MYH11A |
Interacting Protein
TMOD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMOD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TMOD1.
BUB1;TLR2;ODC1;CDH1;APC;PIK3CA;DCC;CDKN2A;FBXW7;DLC1;MLH3;MYO1C;Itga5;FLNA;CDK2;MYH9;ADD1;IQGAP1
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