Recombinant Human TRAF1 Protein, His/GST-tagged
| Cat.No. : | TRAF1-389H |
| Product Overview : | Recombinant Human TRAF1(Gly131~Ala381) fused with His/GST tag at N-terminal was expressed in E. coli. |
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| Description : | The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His&GST |
| Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
| Molecular Mass : | 58.3kDa |
| Protein length : | Gly131~Ala381 |
| Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
| Purity : | > 90% |
| Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein. |
| Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
| Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
| Reconstitution : | Reconstitute in PBS or others. |
| Gene Name | TRAF1 TNF receptor-associated factor 1 [ Homo sapiens ] |
| Official Symbol | TRAF1 |
| Synonyms | TRAF1; TNF receptor-associated factor 1; EBI6; Epstein-Bar virus-induced protein 6; MGC:10353; |
| Gene ID | 7185 |
| mRNA Refseq | NM_001190945 |
| Protein Refseq | NP_001177874 |
| MIM | 601711 |
| UniProt ID | Q13077 |
Not For Human Consumption!
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