Recombinant Human TKT, His-tagged

• Cat.No.: TKT-30354TH
• Product Overview: Recombinant fragment, corresponding to amino acids 29-540 of Human Transketolase with an N terminal His tag. Predicted MWt: 57 kDa

Specification

• Description: This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 145 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: ATTAAGSGHPTSCCSAAEIMAVLFFHTGKYFDKASYRVYC LLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQ SDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKA FGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMA EQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPS LPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTK NSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTV PFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSI GEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVE LAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSK DDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTI KPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSA VVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQA VRGLITKA
• Sequence Similarities: Belongs to the transketolase family.
• Protein length: 29-540 a.a.

Gene Information

• Gene Name: TKT transketolase [ Homo sapiens ]
• Official Symbol: TKT
• Synonyms: TKT; transketolase; Wernicke Korsakoff syndrome
• Gene ID: 7086
• mRNA Refseq: NM_001064
• Protein Refseq: NP_001055
• MIM: 606781
• Uniprot ID: P29401
• Chromosome Location: 3p14.3
• Pathway: Insulin effects increased synthesis of Xylulose-5-Phosphate, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem
• Function: magnesium ion binding; monosaccharide binding; thiamine pyrophosphate binding; transferase activity; transketolase activity