Description :	The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1. [provided by RefSeq, May 2012].
Source :	HEK293
Species :	Human
Tag :	Myc&DDK
Form :	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass :	104.6 kDa
Purity :	>50 ug/mL as determined by microplate BCA method
Concentration :	>50 ug/mL as determined by microplate BCA method

Gene Name	TJP3 tight junction protein 3 (zona occludens 3) [ Homo sapiens ]
Official Symbol	TJP3
Synonyms	ZO-3; ZO3
Gene ID	27134
mRNA Refseq	NM_014428
Protein Refseq	NP_055243
MIM	612689
UniProt ID	O95049