Recombinant Human THRA, His-tagged

• Cat.No.: THRA-31520TH
• Product Overview: Recombinant full length Human Thyroid Hormone Receptor alpha 1, with His tag expressed in a baculovirus system, approximately 54kDa, amino acids 1-490,

Specification

• Species: Human
• Tag: His
• Protein Length: 1-490 a.a.
• Description: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
• Conjugation: HIS
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Full Length: Full L.

Gene Information

• Gene Name: THRA thyroid hormone receptor, alpha [ Homo sapiens ]
• Official Symbol: THRA
• Synonyms: THRA; thyroid hormone receptor, alpha; ERBA1, THRA1, THRA2, thyroid hormone receptor, alpha (avian erythroblastic leukemia viral (v erb a) oncogene homolog) , thyroid hormone receptor, alpha (erythroblastic leukemia viral (v erb a) oncogene homolog, avi
• Gene ID: 7067
• mRNA Refseq: NM_001190918
• Protein Refseq: NP_001177847
• MIM: 190120
• Uniprot ID: P10827
• Chromosome Location: 17q21.1
• Pathway: Endochondral Ossification, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem
• Function: TBP-class protein binding; metal ion binding; protein binding; protein domain specific binding; receptor activity