Recombinant Human TFE3

• Cat.No.: TFE3-218H
• Product Overview: Recombinant Human TFE-3 protein expressed inE.coliencodes 318-476 amino acids and has a molecular mass of 43 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: The DNA-binding factor TFE-3 contains adjacent helix-loop-helix (HLH) and leucine zipper (LZ) domains flanked by an upstream basic region. TFE-3 is ubiquitously expressed and can directly associates with DNA as either homodimers or heterodimers formed with two related proteins, TFEB or TFEC. TFE-3 binds to and activates the microE3 motif of the immunoglobulin heavy-chain enhancer to induce B-cell specific gene transcription and DNA recombination.
• Formulation: Recombinant Human TFE-3 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
• Application And Suggested Dilutions: ELISA, Inhibition Assays, Western Blotting.
• Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 43 kDa.
• Storage & Stability: Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.

Gene Information

• Gene Name: TFE3 transcription factor binding to IGHM enhancer 3 [ Homo sapiens ]
• Synonyms: TFE3; transcription factor binding to IGHM enhancer 3; TFEA; RCCP2; bHLHe33; transcription factor E family, member A; TFECL; hTFEC-L; bHLHe34; Protein TFE-C; Transcription factor EC-like; transcription factor EC; Transcription factor E3
• Gene ID: 7030
• mRNA Refseq: NM_006521
• Protein Refseq: NP_006512
• MIM: 314310
• UniProt ID: P19532
• Chromosome Location: Xp11.22
• Function: promoter binding; protein binding; transcription factor activity