Recombinant Human TDGF1, MBP

• Cat.No.: TDGF1-2904H
• Product Overview: Recombinant Human TDGF1 (1-188 aa) is expressed in E.Coli with MBP.

Specification

• Species: Human
• Source: E.coli
• Tag: MBP
• Protein Length: 1-188 a.a.
• Description: Teratocarcinoma-derived growth factor 1 is the founding member of the EGF-CFC gene family, which is conserved among vertebrates. Proteins within this family contain a signal sequence, a characteristic EGF-like domain, a cysteine-rich region termed the cryptic (CFC) motif, and a hydrophobic C-terminus. It has been reported that Cripto-1 is O-fucosylated on Thr-88 and that this modification is required for the physical interaction with Nodal as well as for signalling activity. We have confirmed that teratocarcinoma-derived growth factor 1 is O-fucosylated at this site.
• MW: 65835 Da.
• Formulation: Lyophilized from a solution of phosphate buffered saline (PBS), pH 7.4 purified by affinity chromatography.
• Application: ELISA, WB, Antibody Production, Protein array.

Gene Information

• Synonyms: TDGF1; teratocarcinoma-derived growth factor 1; CR; CRGF; CRIPTO; Cripto-1; Epidermal growth factor-like cripto protein CR1; Cripto-1 growth factor
• Gene ID: 6997
• mRNA Refseq: NM_003212
• Protein Refseq: NP_003203
• MIM: 187395
• UniProt ID: P13385
• Chromosome Location: 3p21.31
• Function: growth factor activity