Recombinant Human STIP1 Protein, DDK-tagged

• Cat.No.: STIP1-252H
• Product Overview: Recombinant Human STIP1 fused with DDK tag at C-terminal was expressed in in Sf9 cells.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: Flag
• Description: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).
• Form: 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol. Store at -80centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 62.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: STIP1 stress-induced-phosphoprotein 1 [ Homo sapiens ]
• Official Symbol: STIP1
• Synonyms: STIP1; stress-induced-phosphoprotein 1; HOP; Hsp70/Hsp90 organizing protein; STI1; NY-REN-11 antigen; Hsp70/Hsp90-organizing protein; hsc70/Hsp90-organizing protein; renal carcinoma antigen NY-REN-11; transformation-sensitive protein IEF SSP 3521; P60; STI1L; IEF-SSP-3521
• Gene ID: 10963
• mRNA Refseq: NM_006819
• Protein Refseq: NP_006810
• MIM: 605063
• UniProt ID: P31948