Recombinant Human SRI, His-tagged

• Cat.No.: SRI-3478H
• Product Overview: Recombinant human SRI protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Cat. No.: SRI-3478H
• Description: Sorcin, also known as SRI, is a 22-kDa calcium-binding protein initially identified in multidrug-resistant cells. SRI modulates excitation-contraction coupling in the heart and contributes to calcium homeostasis in the heart sarcoplasmic reticulum.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.2M NaCl, 1mM DTT, 0.1mM PMSF
• Molecular Weight: 24.1 kDa (221aa) confirmed by MALDI-TOF
• Purity: > 90% by SDS - PAGE
• Concentration: 0.5 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSMAYPGHP GAGGGYYPGG YGGAPGGPAF PGQTQDPLYG YFAAVAGQDG QIDADELQRC LTQSGIAGGY KPFNLETCRL MVSMLDRDMS GTMGFNEFKE LWAVLNGWRQ HFISFDTDRS GTVDPQELQK ALTTMGFRLS PQAVNSIAKR YSTNGKITFD DYIACCVKLR ALTDSFRRRD TAQQGVVNFP YDDFIQCVMS V
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: SRI sorcin [ Homo sapiens ]
• Synonyms: CP22; SRI; V19; CP-22; H_RG167B05.1; 22 kDa protein;calcium binding protein amplified in mutlidrug-resistant cells; OTTHUMP00000205590; Sorcin; SCN; FLJ26259;OTTHUMP00000206386; OTTHUMP00000213080
• Gene ID: 6717
• mRNA Refseq: NM_003130
• Protein Refseq: NP_003121
• MIM: 182520
• UniProt ID: P30626
• Chromosome Location: 7q21.1
• Function: calcium channel regulator activity; calcium ion binding; receptor binding