SRI

  • Official Full Name

    sorcin
  • Overview

    Sorcin, also known as SRI, is a 22-kDa calcium-binding protein initially identified in multidrug-resistant cells. SRI modulates excitation-contraction coupling in the heart and contributes to calcium homeostasis in the heart sarcoplasmic reticulum.
  • Synonyms

    SRI;sorcin;22 kDa protein;Calcium binding protein amplified in mutlidrug resistant cells;CP 22;CP-22;CP22;SCN;Sorcin (class 4 gene);SORCN_HUMAN;V19;H_RG167B05.1;OTTHUMP00000161663;OTTHUMP00000205590;OTTHUMP00000206386;OTTHUMP00000213080;OTTHUMP00000225575;calcium binding protein amplified in mutlidrug-resistant cells

Recombinant Proteins

  • Human
  • Zebrafish
  • Mouse
  • Chicken
  • Rhesus macaque
  • Cynomolgus
  • E.coli
  • Mammalian Cells
  • Insect Cells
  • HEK293
  • His
  • GST
  • Non
  • Flag
  • Twin Strep
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
SRI-2953H Recombinant Human SRI, His-tagged E.coli Human His 1-198aa
SRI-10691Z Recombinant Zebrafish SRI Mammalian Cells Zebrafish His
SRI-15983M Recombinant Mouse SRI Protein Mammalian Cells Mouse His
SRI-3478H Recombinant Human SRI, His-tagged E.coli Human His
SRI-3622C Recombinant Chicken SRI Mammalian Cells Chicken His
SRI-4465R Recombinant Rhesus monkey SRI Protein, His-tagged Mammalian Cells Rhesus macaque His
SRI-492H Recombinant Human SRI, None tagged Insect Cells Human His 1-198 a.a.
SRI-8653H Recombinant Human SRI protein(Met1-Val198), His&GST-tagged Insect Cells Human GST&His Met1-Val198
SRI-975C Recombinant Cynomolgus SRI Protein, His-tagged Mammalian Cells Cynomolgus His
SRI-001HCL Recombinant Human SRI cell lysate Insect Cells Human Non
SRI-003H Recombinant Full Length Human sorcin Protein, His&Flag&StrepII tagged E.coli Human Flag&His&Twin Strep Full L. 1-198aa
SRI-1882H Recombinant Human SRI Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
SRI-1986H Recombinant Human SRI protein Insect Cells Human Non Met1-Val198
SRI-3527H Recombinant Human SRI protein, GST-tagged E.coli Human GST 1-198aa
Sri-420M Recombinant Mouse Sri Protein, MYC/DDK-tagged HEK293 Mouse DDK&Myc
SRI-4281R Recombinant Rhesus Macaque SRI Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
SRI-4281R-B Recombinant Rhesus Macaque SRI Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
SRI-718C Recombinant Cynomolgus Monkey SRI Protein, His (Fc)-Avi-tagged HEK293 Cynomolgus Avi&Fc&His
SRI-718C-B Recombinant Cynomolgus Monkey SRI Protein Pre-coupled Magnetic Beads HEK293 Cynomolgus
SRI-8717M Recombinant Mouse SRI Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
SRI-8717M-B Recombinant Mouse SRI Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SRI involved in several pathways and played different roles in them. We selected most pathways SRI participated on our site, such as Ion channel transport,Stimuli-sensing channels,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRI were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ion channel transport SGK2,ANO9,PDZD11,CUTC,CLCN1A,ATP13A1,TTYH2,ATP13A,TRPC4APB,TRPC4
    Transmembrane transport of small molecules SLC6A5,ATP1A1A.2,SLC6A15,SLC6A20B,SLC9A3.2,LCN12,SLC9A9,SLC28A2,SLC22A18,SLC17A1
    Stimuli-sensing channels Ano3,TRDN,TRPM1B,SLC17A3,NHEDC1,TPCN1,ASPH,TRPC4APA,CLCN5,ANO5

    Protein Function

    SRI has several biochemical functions, for example, calcium channel regulator activity,calcium ion binding,calcium-dependent cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SRI itself. We selected most functions SRI had, and list some proteins which have the same functions with SRI. You can find most of the proteins on our site.

    Function Related Protein
    protein binding LRRC26,C16orf53,HMG20B,SBDS,UBE2D2A,QKI,PGBD1,PPIE,TEN1,SRGAP1
    repressing transcription factor binding TBP,ARNTL,TCF3,CBX5,HDAC9,KAT5,HHEX,MAGEA2B,MYC,RELA
    receptor binding APOL2,FGF10B,HAMP,Icosl,TRDN,ICAM3,MLYCD,MAP7,NTF7,STOML2
    protein heterodimerization activity ABCG8,EXT2,PEF1,KCNIP1,SFRP5,CAV1,HER5,H2AFB2,SNX6,BRAF
    identical protein binding CEP57L1,CCDC91,PIK3AP1,DYNLT1A,PIP4K2C,PRPS2,FTL,SERPINA1E,G6PDX,TPRGL
    ion channel binding ACTN1,CALM3,SCN5A,AASS,SLC14A2,PRNP,S100A10,FKBP1B,RYR2,RIMS1
    protease binding PINK1,ITGB1,ADAM8A,ADRM1,PANX1,BRCA2,SERPINB9,ALPI,SERPINB4,CFLAR
    calcium-dependent cysteine-type endopeptidase activity CAPN5A,CAPN5,CAPNS1A,CAPN2L,PDCD6,CAPNS1B,CAPN9,CAPN3,PEF1,CAPN13
    calcium channel regulator activity PRKG1,PLN,NRXN1,TSPAN13,CACNA2D1A,CACNB2,GRM2A,SGK1,GNB2,NRXN3

    Interacting Protein

    SRI has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRI here. Most of them are supplied by our site. Hope this information will be useful for your research of SRI.

    CALCOCO2;PDE4C;TCF12;PRR13;PSEN2;VCAM1;STAT3

    Resources

    References

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