Recombinant Human SPARC related modular calcium binding 1 Protein, His tagged

• Cat.No.: SMOC1-024H
• Product Overview: Recombinant human SMOC-1 protein (Q9H4F8) (His 27-Val 434) with a His tag at the C-terminus was expressed in HEK293.

Specification

• Description: SPARC-related modular calcium-binding protein 1, also known as secreted modular calcium-binding protein 1 and SMOC1, is a member of the SPARC family. SMOC1 is widely expressed in many tissues with a strongest signal in ovary. It contains two EF-hand domains, one Kazal-like domain and two thyroglobulin type-1 domains. Extracellular matrix proteins have been implicated in the regulation of osteoblast differentiation of bone marrow-derived mesenchymal stem cells (BMSCs) through paracrine or autocrine mechanisms. SMOC1 is a regulator of osteoblast differentiation of BMSCs. SMOC1 is highly expressed and secreted in BMSCs stimulated with osteogenic medium (OSM). SMOC1 and SMOC2 are matricellular proteins thought to influence growth factor signaling, migration, proliferation, and angiogenesis. SMOC1 and SMOC2 may mediate intercellular signaling and cell type-specific differentiation during gonad and reproductive tract development.
• Source: HEK293
• Species: Human
• Tag: C-His
• Protein length: 27-434aa
• Molecular Mass: 46.7 kDa
• Endotoxin: Less than 1.0 EU/μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
• Reconstitution: Reconstitute at 250 μg/mL in sterile water.

Gene Information

• Gene Name: SMOC1 SPARC related modular calcium binding 1 [ Homo sapiens (human) ]
• Official Symbol: SMOC1
• Synonyms: SMOC1; SPARC related modular calcium binding 1; SPARC-related modular calcium-binding protein 1; secreted modular calcium-binding protein 1; OAS
• Gene ID: 64093
• mRNA Refseq: NM_001034852
• Protein Refseq: NP_001030024
• MIM: 608488
• UniProt ID: Q9H4F8