Recombinant Human SNCA Protein

• Cat.No.: SNCA-02H
• Product Overview: Human Recombinant Alpha Synuclein Oligomers (Dopamine HCL Stabilized) without tag was expressed in E. coli.

Specification

• Description: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
• Source: E. coli
• Species: Human
• Purity: > 95% pure using SDS-PAGE analysis.
• Applications: WB, SDS-PAGE, In vivo assay, In vitro assay
• Storage: At -80 centigrade.
• Storage Buffer: PBS, pH 7.4.
• Shipping: Dry Ice.
  Shipping note: Product will be shipped separately from other products purchased in the same order.

Gene Information

• Gene Name: SNCA synuclein alpha [ Homo sapiens (human) ]
• Official Symbol: SNCA
• Synonyms: SNCA; synuclein alpha; PD1; NACP; PARK1; PARK4; alpha-synuclein; I+/--synuclein; non A-beta component of AD amyloid; synuclein alpha-140; synuclein, alpha (non A4 component of amyloid precursor); truncated alpha synuclein
• Gene ID: 6622
• mRNA Refseq: NM_000345
• Protein Refseq: NP_000336
• MIM: 163890
• UniProt ID: P37840