Recombinant Human SMARCA2 Protein (636-1131), N-FLAG tagged

• Cat.No.: SMARCA2-11H
• Product Overview: Recombinant SMARCA2 protein that includes amino acids 636-1131 of human SMARCA2 protein (accession number NP_001276325.1) was expressed in a baculovirus expression system, and contains an N-terminal FLAG tag.

Specification

• Description: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.
• Source: Baculovirus
• Species: Human
• Tag: Flag
• Molecular Mass: 82.5 kDa
• Protein length: 636-1131
• Purity: ≥ 90%
• Storage: Recombinant proteins in solution are temperature sensitive and must be stored at -80 centigrade to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
• Concentration: 0.6 μg/μL
• Storage Buffer: 25 mM HEPES-NaOH pH 7.5, 300 mM NaCI, 10% glycerol, 0.04% Triton X-100, 0.5 mM TCEP

Gene Information

• Gene Name: SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 [ Homo sapiens (human) ]
• Official Symbol: SMARCA2
• Synonyms: SMARCA2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2; BIS; BRM; SNF2; SWI2; hBRM; NCBRS; Sth1p; BAF190; SNF2L2; SNF2LA; hSNF2a; probable global transcription activator SNF2L2; ATP-dependent helicase SMARCA2; BAF190B; BRG1-associated factor 190B; SNF2-alpha; SNF2/SWI2-like protein 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2; brahma homolog; global transcription activator homologous sequence; protein brahma homolog; putative global transcription activator SNF2L2; sucrose nonfermenting 2-like protein 2
• Gene ID: 6595
• mRNA Refseq: NM_001289396
• Protein Refseq: NP_001276325
• MIM: 600014
• UniProt ID: P51531