Recombinant Human SIRT2 Protein, His-tagged
Cat.No. : | SIRT2-23H |
Product Overview : | Recombinant human SIRT2(2-389) protein with a N-terminal His-tag was expressed in E. coli. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | 2-389 |
Description : | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. |
Molecular Mass : | 44.2 kDa |
Purity : | ≥90% estimated by SDS-PAGE |
Unit Definition : | One unit is defined as the amount of enzyme required to produce 1 nmol of 7-amino-4-methylcouarin per minute at 25 centigrade in 50 mM Tris-HCl, pH 8.0, 137 mM NaCl, 2.7 mM KCl, 1 mM MgCl2, containing 125 μM p53 amino acids 317-320 (Gln-Pro-Lys-Lys(e-acetyl)-AMC), and 6 mM NAD+. |
Stability : | ≥ 1 year |
Storage : | Store it at -80 centigrade |
Storage Buffer : | 50 mM sodium phosphate, pH 7.2, containing 100 mM sodium chloride and 20% glycerol |
Gene Name | SIRT2 sirtuin 2 [ Homo sapiens (human) ] |
Official Symbol | SIRT2 |
Synonyms | SIRT2; sirtuin 2; SIR2; SIR2L; SIR2L2; NAD-dependent protein deacetylase sirtuin-2; NAD-dependent deacetylase sirtuin-2; SIR2-like protein 2; regulatory protein SIR2 homolog 2; silent information regulator 2; sir2-related protein type 2; sirtuin type 2 |
Gene ID | 22933 |
mRNA Refseq | NM_001193286 |
Protein Refseq | NP_001180215 |
MIM | 604480 |
UniProt ID | Q8IXJ6 |
◆ Recombinant Proteins | ||
SIRT2-23H | Recombinant Human SIRT2 Protein, His-tagged | +Inquiry |
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◆ Cell & Tissue Lysates | ||
SIRT2-1834HCL | Recombinant Human SIRT2 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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