Active Recombinant Human SIRT2 Protein (50-356), C-6xHis tagged

Cat.No. : SIRT2-31405TH
Product Overview : Recombinant Human SIRT2 Protein (50-356) with C-6xHis tag was expressed in E. coli.
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Species : Human
Source : E.coli
Tag : His
Protein Length : 50-356
Description : This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.
Form : Aqueous buffer solution
Bio-activity : ≥1.0 pmol/min/μg.
Molecular Mass : 36 kDa
Purity : ≥90%
Applications : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Usage : Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage.
Storage : At least 6 months at -80 centigrade.
Storage Buffer : 40 mM Tris, pH 8.0, 110 mM NaCl, 2.1 mM KCl, and 20% glycerol.
Shipping : At -80 centigrade.
Warning : Avoid freeze/thaw cycles.
Gene Name SIRT2 sirtuin 2 [ Homo sapiens (human) ]
Official Symbol SIRT2
Synonyms SIRT2; sirtuin 2; SIR2; SIR2L; SIR2L2; NAD-dependent protein deacetylase sirtuin-2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein defatty-acylase sirtuin-2; SIR2-like protein 2; regulatory protein SIR2 homolog 2; silent information regulator 2; sir2-related protein type 2; sirtuin type 2; EC 2.3.1.286
Gene ID 22933
mRNA Refseq NM_012237
Protein Refseq NP_036369
MIM 604480
UniProt ID Q8IXJ6

Not For Human Consumption!

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