Active Recombinant Human SIRT2 Protein (50-356), C-6xHis tagged
Cat.No. : | SIRT2-31405TH |
Product Overview : | Recombinant Human SIRT2 Protein (50-356) with C-6xHis tag was expressed in E. coli. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | 50-356 |
Description : | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. |
Form : | Aqueous buffer solution |
Bio-activity : | ≥1.0 pmol/min/μg. |
Molecular Mass : | 36 kDa |
Purity : | ≥90% |
Applications : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Usage : | Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage. |
Storage : | At least 6 months at -80 centigrade. |
Storage Buffer : | 40 mM Tris, pH 8.0, 110 mM NaCl, 2.1 mM KCl, and 20% glycerol. |
Shipping : | At -80 centigrade. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name | SIRT2 sirtuin 2 [ Homo sapiens (human) ] |
Official Symbol | SIRT2 |
Synonyms | SIRT2; sirtuin 2; SIR2; SIR2L; SIR2L2; NAD-dependent protein deacetylase sirtuin-2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein defatty-acylase sirtuin-2; SIR2-like protein 2; regulatory protein SIR2 homolog 2; silent information regulator 2; sir2-related protein type 2; sirtuin type 2; EC 2.3.1.286 |
Gene ID | 22933 |
mRNA Refseq | NM_012237 |
Protein Refseq | NP_036369 |
MIM | 604480 |
UniProt ID | Q8IXJ6 |
◆ Recombinant Proteins | ||
SIRT2-31405TH | Active Recombinant Human SIRT2 Protein (50-356), C-6xHis tagged | +Inquiry |
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SIRT2-5408R | Recombinant Rat SIRT2 Protein | +Inquiry |
SIRT2-5067R | Recombinant Rat SIRT2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
SIRT2-1834HCL | Recombinant Human SIRT2 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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