Recombinant Human SHMT2 Protein, His-tagged

• Cat.No.: SHMT2-927H
• Product Overview: Recombinant Human SHMT2 fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Tag: His
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 56
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) [ Homo sapiens ]
• Official Symbol: SHMT2
• Synonyms: SHMT2; serine hydroxymethyltransferase 2 (mitochondrial); SHMT; serine hydroxymethyltransferase, mitochondrial; GLY A+; serine aldolase; serine methylase; threonine aldolase; serine hydroxymethylase; glycine hydroxymethyltransferase; glycine auxotroph A, human complement for hamster; GLYA
• Gene ID: 6472
• mRNA Refseq: NM_001166356
• Protein Refseq: NP_001159828
• MIM: 138450
• UniProt ID: P34897