Recombinant Human SETBP1 Protein, His&GST-tagged

• Cat.No.: SETBP1-2054H
• Product Overview: Recombinant Human SETBP1 Protein (Gly1297-Pro1596) with N-His&GST tag was expressed in E. coli.

Specification

• Description: This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 63.3 kDa
  Accurate Molecular Mass: 55 kDa
• Protein length: Gly1297-Pro1596
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: SETBP1 SET binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: SETBP1
• Synonyms: SETBP1; SET binding protein 1; SET-binding protein; KIAA0437; SEB; DKFZp666J1210
• Gene ID: 26040
• mRNA Refseq: NM_001130110
• Protein Refseq: NP_001123582
• MIM: 611060
• UniProt ID: Q9Y6X0