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SETBP1

Official Full Name

SET binding protein 1
Overview

This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms

SETBP1; SET binding protein 1; SET-binding protein; KIAA0437; SEB; SETBP 1;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SETBP1-1587HCL	Recombinant Human SETBP1 cell lysate		Non		Inquiry
Human	SETBP1-996H	Recombinant Human SETBP1 Protein, MYC/DDK-tagged	HEK293	Myc&DDK		Inquiry
Human	SETBP1-2054H	Recombinant Human SETBP1 Protein, His&GST-tagged	E.coli	His&GST	Gly1297-Pro1596	Inquiry
Human	SETBP1-6550H	Recombinant Human SETBP1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK		Inquiry
Mouse	Setbp1-5798M	Recombinant Mouse Setbp1 Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

SETBP1 involved in several pathways and played different roles in them. We selected most pathways SETBP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SETBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

SETBP1 has several biochemical functions, for example, DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SETBP1 itself. We selected most functions SETBP1 had, and list some proteins which have the same functions with SETBP1. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	HIST1H2AF;POLRMT;SATB1A;NR5A5;RORCA;PAX4;NR1D4B;NR5A1;HIST1H2B7
protein binding	CERS2;MPL;FHIT;EEF1D;NADSYN1;NKRF;KRTAP19-7;XRN1;CDC27

SETBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SETBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SETBP1.

g2xkq0_human; UBE2I; YAF2; SPANXD; PLEKHF2; XAGE1A

Research Area

Kim, JT; Liu, CM; et al. Neurotensin, a novel target of Wnt/beta-catenin pathway, promotes growth of neuroendocrine tumor cells. INTERNATIONAL JOURNAL OF CANCER 136:1475-1481(2015).

Angeletti, D; Sandalova, T; et al. Binding of Subdomains 1/2 of PfEMP1-DBL1 alpha to Heparan Sulfate or Heparin Mediates Plasmodium falciparum Rosetting. PLOS ONE 10:-(2015).