Recombinant Human SERPINB6 Protein, MYC/DDK-tagged

• Cat.No.: SERPINB6-1009H
• Product Overview: Recombinant human SERPINB6 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 42.4 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 [ Homo sapiens ]
• Official Symbol: SERPINB6
• Synonyms: CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3
• Gene ID: 5269
• mRNA Refseq: NM_001195291
• Protein Refseq: NP_001182220
• MIM: 173321
• UniProt ID: P35237