Recombinant Human SENP7 Protein (T640-P984), GST tagged

• Cat.No.: SENP7-0884H
• Product Overview: Recombinant Human GST-TEV-GG-SENP7(T640-P984) Protein was expressed in E. coli.

Specification

• Description: Protease that acts as a positive regulator of the cGAS-STING pathway by catalyzing desumoylation of CGAS. Desumoylation of CGAS promotes DNA-binding activity of CGAS, subsequent oligomerization and activation. Deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Liquid
• Protein length: T640-P984
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: SENP7 SUMO1/sentrin specific peptidase 7 [ Homo sapiens (human) ]
• Official Symbol: SENP7
• Synonyms: SENP7; SUMO1/sentrin specific peptidase 7; SUMO1/sentrin specific protease 7; sentrin-specific protease 7; SUMO-1-specific protease 2; sentrin/SUMO-specific protease SENP7; KIAA1707; MGC157730
• Gene ID: 57337
• mRNA Refseq: NM_001077203
• Protein Refseq: NP_001070671
• MIM: 612846
• UniProt ID: Q9BQF6