SENP7
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Official Full Name
SUMO1/sentrin specific peptidase 7 -
Overview
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see;SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO;precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display;isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 (PubMed;18799455)). -
Synonyms
SENP7;SUMO1/sentrin specific peptidase 7;SUMO1/sentrin specific protease 7;sentrin-specific protease 7;SUMO-1-specific protease 2;sentrin/SUMO-specific protease SENP7;KIAA1707;MGC157730
Recombinant Proteins
- Human
- Rat
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SENP7-405H | Recombinant Human SENP7 Protein, His-tagged | E.coli | Human | His | 630-799 a.a. |
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| SENP7-5318R | Recombinant Rat SENP7 Protein | Mammalian Cell | Rat | His |
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| SENP7-7915H | Recombinant Human SENP7 | E.coli | Human | Non |
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| SENP7-1971HCL | Recombinant Human SENP7 293 Cell Lysate | HEK293 | Human | Non |
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| SENP7-1972HCL | Recombinant Human SENP7 293 Cell Lysate | HEK293 | Human | Non |
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| SENP7-0883H | Recombinant Human SENP7 Protein (T640-P984), Tag Free | E.coli | Human | Non | T640-P984 |
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| SENP7-0884H | Recombinant Human SENP7 Protein (T640-P984), GST tagged | E.coli | Human | GST | T640-P984 |
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| SENP7-4977R | Recombinant Rat SENP7 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SENP7-4977R-B | Recombinant Rat SENP7 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| SENP7-6065H | Recombinant Human SENP7 Protein (Met695-Ala864), N-His tagged | E.coli | Human | His | Met695-Ala864 |
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Involved Pathway
SENP7 involved in several pathways and played different roles in them. We selected most pathways SENP7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SENP7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SENP7 has several biochemical functions, for example, cysteine-type peptidase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SENP7 itself. We selected most functions SENP7 had, and list some proteins which have the same functions with SENP7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cysteine-type peptidase activity | CASP6,CTSL2,ZRANB1B,SENP3B,CAPN5A,CTSLA,FAM49BA,ATG4A,CTSH,CTSJ |
| protein binding | COX17,CHRAC1,DCAF12L1,CARD10,AGTR1,RPL7A,B3GAT3,CXCR2,GADD45A,HDAC7 |
Interacting Protein
SENP7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SENP7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SENP7.
CBX5;TRIM28;BCL6
Resources
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References
- Romeo, K; Louault, Y; et al. The SENP7 SUMO-Protease Presents a Module of Two HP1 Interaction Motifs that Locks HP1 Protein at Pericentric Heterochromatin. CELL REPORTS 10:771-782(2015).
- Alegre, KO; Reverter, D; et al. Structural insights into the SENP6 Loop1 structure in complex with SUMO2. PROTEIN SCIENCE 23:433-441(2014).
