Recombinant Human RNASE3 Protein (Pro30-Val154), His tagged

• Cat.No.: RNASE3-5069H
• Product Overview: Recombinant human RNASE3 (Pro30-Val154) fused with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Pro30-Val154
• Description: Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA) . RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E. coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 16.02 kDa
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: RNASE3 ribonuclease, RNase A family, 3 [ Homo sapiens (human) ]
• Official Symbol: RNASE3
• Synonyms: RNASE3; ribonuclease, RNase A family, 3; RNS3; eosinophil cationic protein; ECP; RNase 3; ribonuclease 3; cytotoxic ribonuclease
• Gene ID: 6037
• mRNA Refseq: NM_002935
• Protein Refseq: NP_002926
• MIM: 131398
• UniProt ID: P12724