Native Human Ribonuclease, RNase A Family, 3

• Cat.No.: RNASE3-5318H
• Product Overview: NativeHuman RNASE3 was expessed in Human Eosinophils. Itsmolecular weight is 18000-22000 Dalton (3 glycosolated forms exists).

Specification

• Species: Human
• Source: Human Eosinophils
• Tag: Non
• Description: Native human RNASE3is a secretory ribonuclease found in eosinophilic leukocytes and involved inthe innate immune system. Its cytotoxic activity is effective against a widerange of pathogens, suggesting a relatively non-specific mechanism of action.
• Form: Liquid in 50 mMammonium acetate, pH 4.7 + 0.2 M NaCl
• Concentration: Typically>1.0 mg/mL
• Molecular Weight: 18-22kDa (3 glycosolated forms exists)
• Purity: >98% by SDS-PAGE
• Storage: Store at 2-4°C.
• OfficialSymbol: RNASE3
• Pathways: Asthma

Gene Information

• Gene Name: RNASE3 ribonuclease, RNase A family, 3 [ Homosapiens ]
• Synonyms: RNASE3; ribonuclease,RNase A family, 3; ECP; RNS3; eosinophil cationic protein; EC 3.1.27.-; Eosinophilcationic protein; RNase 3; Ribonuclease 3
• Gene ID: 6037
• mRNA Refseq: NM_002935
• Protein Refseq: NP_002926
• MIM: 131398
• UniProt ID: P12724
• Chromosome Location: 14q24-q31
• Function: endonucleaseactivity; hydrolase activity; nucleic acid binding; pancreatic ribonucleaseactivity; ribonuclease activity