Recombinant Human RBP4

• Cat.No.: RBP4-31234TH
• Product Overview: Recombinant human RBP4 was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 19-201aa
• Description: This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.
• Form: In Phosphate-Buffered Saline (pH 7.4)
• Molecular Mass: 21 kDa (184 aa), confirmed by MALDI-TOF.
• AA Sequence: MERDCRVSSF RVKENFDKAR FSGTWYAMAK KDPEGLFLQD NIVAEFSVDE TGQMSATAKG RVRLLNNWDV CADMVGTFTD TEDPAKFKMKYWGVASFLQK GNDDHWIVDT DYDTYAVQYS CRLLNLDGTC ADSYSFVFSR DPNGLPPEAQ KIVRQRQEEL CLARQYRLIV HNGYCDGRSERNLL
• Endotoxin: < 1.0 Eu per 1 microgram of protein (determined by LAL method)
• Purity: > 95% by SDS - PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: RBP4 retinol binding protein 4, plasma [ Homo sapiens ]
• Official Symbol: RBP4
• Synonyms: RBP4; retinol binding protein 4, plasma; OTTHUMP00000020116; retinol-binding protein 4, interstitial; RBP; Plasma retinol-binding protein(1-182); Plasma retinol-binding protein(1-181); Plasma retinol-binding protein(1-179); OTTHUMP00000020114
• Gene ID: 5950
• mRNA Refseq: NM_006744
• Protein Refseq: NP_006735
• MIM: 180250
• UniProt ID: P02753
• Chromosome Location: 10q23.33
• Pathway: Diseases associated with visual transduction; Retinoid metabolism and transport; The canonical retinoid cycle in rods (twilight vision)
• Function: protein binding; protein heterodimerization activity; retinal binding