Recombinant Human RARA, His-tagged

Cat.No. : RARA-31320TH
Product Overview : Recombinant fragment, corresponding to amino acids 150-417 of His tagged, Human Retinoic Acid Receptor alpha. Predicted MW 34 kDA,
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Species : Human
Source : E.coli
Tag : His
Protein Length : 150-417 a.a.
Description : This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.
Conjugation : HIS
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the nuclear hormone receptor family. NR1 subfamily.Contains 1 nuclear receptor DNA-binding domain.
Gene Name RARA retinoic acid receptor, alpha [ Homo sapiens ]
Official Symbol RARA
Synonyms RARA; retinoic acid receptor, alpha; retinoic acid receptor alpha; NR1B1; RAR;
Gene ID 5914
mRNA Refseq NM_000964
Protein Refseq NP_000955
MIM 180240
Uniprot ID P10276
Chromosome Location 17q21.1
Pathway Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adipogenesis, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem;
Function chromatin DNA binding; enzyme binding; metal ion binding; protein binding; protein domain specific binding;

Not For Human Consumption!

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