Recombinant Human RALGDS, MYC/DDK-tagged

• Cat.No.: RALGDS-2169H
• Product Overview: Recombinant Human RALGDS, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.
• Molecular Mass: 100.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: RALGDS ral guanine nucleotide dissociation stimulator [ Homo sapiens ]
• Official Symbol: RALGDS
• Synonyms: RALGDS; ral guanine nucleotide dissociation stimulator; RalGEF; RGDS; RGF; ral guanine nucleotide exchange factor
• Gene ID: 5900
• mRNA Refseq: NM_006266
• Protein Refseq: NP_006257
• MIM: 601619
• UniProt ID: Q12967
• Chromosome Location: 9q34.3
• Pathway: Colorectal cancer; Pancreatic cancer; Pathways in cancer
• Function: guanyl-nucleotide exchange factor activity; small GTPase regulator activity; protein binding