Recombinant Human RALGDS, GST-tagged

• Cat.No.: RALGDS-30899TH
• Product Overview: Recombinant Human RALGDS, Ras-binding domain (RBD) of the human RalGDS, comprises amino acids 788-885 (97aa) of wild type, was expressed in E. coli with GST tag.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 788-885 a.a.
• Description: Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.
• Form: Liquid (Supplied in 30 mM Tris-HCl pH 7.5, 100 mM NaCl, 5 mM MgCl2 and 5 mM DTE)
• Purity: > 90 % (SDS-PAGE)
• Storage: Store at -80 °C. Avoid freeze/thaw cycles

Gene Information

• Gene Name: RALGDS ral guanine nucleotide dissociation stimulator [ Homo sapiens ]
• Official Symbol: RALGDS
• Synonyms: RALGDS; ral guanine nucleotide dissociation stimulator; RalGEF; RGDS; RGF; ral guanine nucleotide exchange factor
• Gene ID: 5900
• mRNA Refseq: NM_006266
• Protein Refseq: NP_006257
• MIM: 601619
• UniProt ID: Q12967
• Chromosome Location: 9q34.3
• Pathway: Colorectal cancer; Pancreatic cancer; Pathways in cancer
• Function: guanyl-nucleotide exchange factor activity; small GTPase regulator activity; protein binding