Recombinant Human RAB34, Member RAS Oncogene Family, His-tagged

• Cat.No.: RAB34-1291H
• Product Overview: Recombinant human RAB34 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: RAB34, also known as ras-related protein Rab34, is localized to the plasma membrane and endocytic compartments and controls a fast endocytic recycling pathway. This protein is involved in protein transport, specifically the redistribution of lysosomes to the peri-Golgi region. In fibroblasts, this protein was colocalized with actin to the membrane ruffles and membranes of relatively large vesicles adjacent to the ruffles.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol 0.1M NaCl,1mM DTT
• Molecular Weight: 31.2 kDa (279aa), confirmed by MALDI-TOF
• Purity: > 90% by SDS - PAGE
• Concentration: 0.5 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MNILAPVRRD RVLAELPQCL RKEAALHGHK DFHPRVTCAC QEHRTGTVGF KISKVIVVGD LSVGKTCLIN RFCKDTFDKN YKATIGVDFE MERFEVLGIP FSLQLWDTAG QERFKCIAST YYRGAQAIII VFNLNDVASL EHTKQWLADA LKENDPSSVL LFLVGSKKDL STPAQYALME KDALQVAQEM KAEYWAVSSL TGENVREFFF RVAALTFEAN VLAELEKSGA RRIGDVVRIN SDDSNLYLTA SKKKPTCCP
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: RAB34 RAB34, member RAS oncogene family [ Homo sapiens ]
• Official Symbol: RAB34
• Synonyms: RAB34; RAB34, member RAS oncogene family; Ras-related protein Rab-39; RAH; RAB39; Ras-related protein Rah; OTTHUMP00000163525
• Gene ID: 83871
• mRNA Refseq: NM_031934
• Protein Refseq: NP_114140
• MIM: 610917
• UniProt ID: Q9BZG1
• Chromosome Location: 17q11.2
• Function: GTP binding; GTPase activity; nucleotide binding; guanyl nucleotide binding