Active Recombinant Human RAB34, Member RAS Oncogene Family, GST-tagged

• Cat.No.: RAB34-1110H

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Description: Rab34 is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. The small GTPase Rab 34 is restricted to cell surface membrane ruffles and lysosmes. It regulates the spatial distribution of lysosomes and is required for formation of macropinosomes. The GST-Tag facilitates the protein's application in typical GST pull-down assays.
• Usage: For in vitro use only.
• Form: Liquid. Supplied in 50 mM Tris-HCl pH 8.0, 100 mM NaCl, 10 mM MgCl2, 10 μM GDP and 2 mM mercaptoethanol.
• Activity: 100 pmol of protein can bind > 80 pmol of GDP.
• Purity: ≥ 90% by SDS-PAGE.
• Storage: Quality guaranteed for 12 months. Store at -80℃. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: RAB34 RAB34, member RAS oncogene family [ Homo sapiens ]
• Synonyms: RAB34; RAB34, member RAS oncogene family; Ras-related protein Rab-39; RAH; RAB39; Ras-related protein Rah; OTTHUMP00000163525
• Gene ID: 83871
• mRNA Refseq: NM_001142624
• Protein Refseq: NP_001136096
• MIM: 610917
• UniProt ID: Q9BZG1
• Chromosome Location: 17q11.2
• Function: GTP binding; GTPase activity; nucleotide binding; guanyl nucleotide binding