Recombinant Human PTPN7,GST-tagged,Active

• Cat.No.: PTPN7-466H
• Product Overview: Recombinant human full length PTPN7 was expressed inE.colicells using a N-terminal GST tag. MW=67kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Description: PTPN7 gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and negatively regulates ERK2 and p38 MAP-kinases activity. The PTPN7 was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway.
• Sequence: Full length.
• Applications: Phosphatase Assay, Western Blot.
• Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Full Length: Full L.

Gene Information

• Gene Name: PTPN7 protein tyrosine phosphatase, non-receptor type 7 [ Homo sapiens ]
• Synonyms: PTPN7; protein tyrosine phosphatase, non-receptor type 7; EC 3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase LC-PTP; LPTP; HEPTP; PTPNI; BPTP-4; LC-PTP; Tyrosine-protein phosphatase non-receptor type 7
• Gene ID: 5778
• mRNA Refseq: NM_002832
• Protein Refseq: NP_002823
• UniProt ID: P35236
• Chromosome Location: 1q32.1
• MIM: 176889
• Pathway: MAPK signaling pathway
• Function: hydrolase activity; protein binding; protein tyrosine phosphatase activity