Recombinant Human PROK1 protein, His & GST-tagged

• Cat.No.: PROK1-592H
• Product Overview: Recombinant Human PROK1 (P58294) aa. (Met1~Phe105) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Met1~Phe105
• Description: The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 44.2kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 90%
• Characteristic: The isoelectric point is 8.1.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in ddH2O.

Gene Information

• Gene Name: PROK1 prokineticin 1 [ Homo sapiens (human) ]
• Official Symbol: PROK1
• Synonyms: PROK1; prokineticin 1; PK1; PRK1; EGVEGF; prokineticin-1; EG-VEGF; black mamba toxin-related protein; endocrine-gland-derived vascular endothelial growth factor; mambakine
• Gene ID: 84432
• mRNA Refseq: NM_032414.2
• Protein Refseq: NP_115790.1
• UniProt ID: P58294