Recombinant Human Phospholipase D2

• Cat.No.: PLD2-683H
• Product Overview: Recombinant human PLD2 (aa 1-274) is expressed inE. coli. MW=56kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 1-274 a.a.
• Description: Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.
• Application: ELISA, Inhibition Assays, Western Blotting.
• Presentation: 100μl purified human PLD2 protein at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol without BSA and Sodium Azide.
• Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 56kDa (including GST).
• Storage: Store vial at -20⁰C to -80℃. When stored at the recommended temperature, this protein is stable for 12 months.

Gene Information

• Gene Name: PLD2 phospholipase D2 [ Homo sapiens ]
• Synonyms: PLD2; phospholipase D2; EC 3.1.4.4; PLD 2; PLD1C; choline phosphatase 2; hPLD2; phosphatidylcholine-hydrolyzing phospholipase D2
• Gene ID: 5338
• mRNA Refseq: NM_002663
• Protein Refseq: NP_002654
• MIM: 602384
• UniProt ID: O14939
• Chromosome Location: 17p13.1
• Pathway: Endocytosis; Ether lipid metabolism; Fc gamma R-mediated phagocytosis; Glycerophospholipid metabolism; GnRH signaling pathway; Metabolic pathways
• Function: NAPE-specific phospholipase D activity; hydrolase activity; phosphoinositide binding; phospholipase D activity; protein binding