Recombinant Human Phospholipase D2
Cat.No. : | PLD2-683H |
Product Overview : | Recombinant human PLD2 (aa 1-274) is expressed inE. coli. MW=56kDa. |
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Species : | Human |
Source : | E.coli |
Tag : | Non |
Protein Length : | 1-274 a.a. |
Description : | Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control. |
Application : | ELISA, Inhibition Assays, Western Blotting. |
Presentation : | 100μl purified human PLD2 protein at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol without BSA and Sodium Azide. |
Characterization : | On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 56kDa (including GST). |
Storage : | Store vial at -200C to -80℃. When stored at the recommended temperature, this protein is stable for 12 months. |
Gene Name | PLD2 phospholipase D2 [ Homo sapiens ] |
Synonyms | PLD2; phospholipase D2; EC 3.1.4.4; PLD 2; PLD1C; choline phosphatase 2; hPLD2; phosphatidylcholine-hydrolyzing phospholipase D2 |
Gene ID | 5338 |
mRNA Refseq | NM_002663 |
Protein Refseq | NP_002654 |
MIM | 602384 |
UniProt ID | O14939 |
Chromosome Location | 17p13.1 |
Pathway | Endocytosis; Ether lipid metabolism; Fc gamma R-mediated phagocytosis; Glycerophospholipid metabolism; GnRH signaling pathway; Metabolic pathways |
Function | NAPE-specific phospholipase D activity; hydrolase activity; phosphoinositide binding; phospholipase D activity; protein binding |
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Not For Human Consumption!
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