Recombinant Human PFN2, His-tagged

• Cat.No.: PFN2-30344TH
• Product Overview: Recombinant full length Human Profilin 2 with an N-terminal His Tag; 160 amino acids with tag, MWt 17.2kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.
• Conjugation: HIS
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAGWQSYVDN LMCDGCCQEA AIVGYCDAKY VWAATAGGVF QSITPIEIDM IVGKDREGFF TNGLALGAKK CSVIRDSLYV DGDCTMDIRT KSQGGEPTYN VAVGRAGRVL VFVMGKEGVH GGGLNKKAYS MAKYLRDSGF
• Full Length: Full L.

Gene Information

• Gene Name: PFN2 profilin 2 [ Homo sapiens ]
• Official Symbol: PFN2
• Synonyms: PFN2; profilin 2; profilin-2
• Gene ID: 5217
• mRNA Refseq: NM_002628
• Protein Refseq: NP_002619
• MIM: 176590
• Uniprot ID: P35080
• Chromosome Location: 3q25.1
• Pathway: Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Regulation of actin cytoskeleton, organism-specific biosystem; Regulation of actin cytoskeleton, conserved biosystem; Salmonella infection, organism-specific biosystem
• Function: actin binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding